Analgesic efficacy of Lysine Clonixinate, paracetamol and dipyrone in lowerthird molar extraction. A randomized controlled trial

Objective: The purpose of this study is to compare the analgesic effect of lysine clonixinate, paracetamol anddipyrone after lower third molar extraction.Material and Methods: The sample consisted of 90 individuals, with clinical indication for inferior third molarsextraction. The mean age of the sample was 22.3 years (DP±2.5). The individuals received the medication in unidentifiedbottles along with the intake instructions. The postoperative pain parameters were measured accordingto Visual Analogical Scale (VAS) and the data was evaluated using the Kruskal-Wallis Test and Friedman Test,with the latter used to test different time intervals for each one of the drugs.Results: The final sample consisted of 64 individuals, including 23 males (45.9%) and 41 females (64.1%) Themean age of the entire sample was 22.3 years (±2.5). The average length of the procedures was 33.9 minutes (±9.8).The distribution of mean values for this variable showed little variance for the different drugs (p=0.07).Conclusion: Lysine Clonixinate did not show any substantial impact on the postoperative pain control when comparedto other drugs (AU)

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Analgesic efficacy of lysine clonixinate, paracetamol and dipyrone in lower third molar extraction: a randomized controlled trial.

OBJECTIVE: The purpose of this study is to compare the analgesic effect of lysine clonixinate, paracetamol and dipyrone after lower third molar extraction. MATERIAL AND METHODS: The sample consisted of 90 individuals with clinical indication for inferior third molar extraction. The mean age of the sample was 22.3 years (DP +/-2.5). The individuals received the medication in unidentified bottles along with the intake instructions. The postoperative pain parameters were measured according to the Visual Analogical Scale (VAS) and the data was evaluated using the Kruskal-Wallis Test and Friedman Test, with the latter used to test different time intervals for each one of the drugs. RESULTS: The final sample consisted of 64 individuals, including 23 males (45.9%) and 41 females (64.1%) The mean age of the entire sample was 22.3 years (+/-2.5). The average length of the procedures was 33.9 minutes (+/-9.8). The distribution of mean values for this variable showed little variance for the different drugs (p=0.07). CONCLUSION: Lysine Clonixinate did not show any substantial impact on the postoperative pain control when compared to other drugs.

Cisto dentígero seqüencial: relato de caso / Sequential dentigerous cyst: case report

O cisto dentígero (CD) é definido como um cisto que se origina pela separação do folículo pericoronáriode um dente incluso devendo estar associado à coroa do mesmo e unido à junção cemento-esmalte.CD seqüencial (CDS) pode ser definido como o desenvolvimento de maneira seqüencial de mais de um cistodentígero em diferentes momentos da vida do paciente. Paciente de 16 anos, sexo masculino, queixando-sede aumento de volume do lado esquerdo da mandíbula com evolução lenta. Após exame físico, radiográficoe histopatológico, foi diagnosticado cisto dentígero. Após 12 anos de controle do paciente, houve aparecimentode imagem radiolucida associada ao dente 48, que teve o diagnóstico de cisto dentígero. Esta descriçãorepresenta um caso raro de CDS. O paciente encontra-se em acompanhamento e após de 16 anos daprimeira ocorrência do CD, não apresenta sinais clínicos e radiográficos de recidivas.

Dentigerous cyst (DC) is originate from separation of dental follicle of the crown of an enclosed tooth,must be associated to the crown of exactly joined to the cementoenamel junction. Sequential DC (SDC)represents the development of DC in sequential way at different moments of one determined period of life ofthe patient. Patient of 16 years, male, complaining of increase of volume of the left side of the jaw with slowevolution. After clinical, radiographic and histopathology exam, the diagnosis of DC was performed. After 12-years follow-up, it was observed a radioluscence, well-defined area associated to the 48 tooth. Also, it wasdiagnosed as DC. This case report represents a rare case of SDC. The patient is free-disease after 16 yearsof follow-up.

Tonsilolito: informe de tres casos clínicos / Tonsillolith: a report of three clinical cases

El tonsilolito es una calcificación distrófica rara que surge como consecuencia de la inflamación crónica de las amígdalas. Se relatan tres casos asintomáticos de tonsilolitos, descubiertos durante el examen radiográfico de rutina por medio de radiografías panorámicas, que mostraron distintos tamaños de imágenes radiopacas, que variaron entre 2 y 5 mm. Los casos I y III presentaron imágenes que no se sobrepusieron a la línea de la mandíbula, lo que condujo a un diagnóstico probable de calcificación de tejido suave. El caso II tenía una imagen radiopaca unilateral, con densidad ósea, sobreponiéndosea la línea de la mandíbula, conduciendo a una lesión benigna intra-ósea, que fue considerada como el diagnóstico diferencial. No se encontraron síntomas en ningún caso. Sólo el caso I tenía características clínicas, mostrando unas placas blancas, visibles a través de la mucosa. Fueron solicitadas tomografías computarizadas de la región maxilo-facial para averiguar la ubicación exacta de estas imágenes, ya que la mayor parte de la superposición de las imágenes radiopacas en la línea mandibular era muy similar a anormalidades intra-óseas. Las tomografías computarizadas mostraron imágenes hiperdensas en las amígdalas palatinas, confirmando el diagnóstico de tonsilolitos. Los pacientes están actualmente en seguimiento. No se requiere tratamiento si no existen síntomas. Concluyendo que los tonsilolitos pueden mostrar imágenesen las radiografías panorámicas similares a alteraciones intra-óseas. El diagnostico es relativamente fácil cuando la tomografía computarizada es solicitada, a pesar de que las imágenes no son patognomónicas

Tonsillolith is a rare dystrophic calcification as a result of chronic inflammation of the tonsils. Three asymptomatic cases of tonsillolith are reported, incidentally discovered through panoramic radiographs, which showed different sizes of radiopaque images, varying from 2 to 5mm; cases I and III images did not overlap the mandible ramus, which led to a probable diagnosis of soft tissue calcification. Case II had radiopaque unilateral images, with osseous tissue density, overlapping the mandibular ramus, leading to a benign intra-osseous lesion, which was considered as differential diagnosis. No symptoms were reported in any case. Only case I had clinical characteristics, showing highly consistent white plaques partially visible through the mucosa. Computed tomography of the maxillofacial region/head and neck were requested to find out the exact location of these images, since most of the overlapping radiopaque images in the mandibular ramus were very similar to intra-osseous abnormalities. The computed tomography showed hyperdense images in the palatine tonsils, confirming the diagnosis of tonsillolith. The patients are currently under follow-up. No treatment is required if there is no symptom. In conclusion, tonsillolith might show images on panoramic radiographs similar to intra osseous abnormalities. The diagnosis is relatively easy when computed tomography is requested, although the images are not pathognomonic. Therefore, clinicians should consider other pathologies as differential diagnosis

Tonsillolith: a report of three clinical cases.

Tonsillolith is a rare dystrophic calcification as a result of chronic inflammation of the tonsils. Three asymptomatic cases of tonsillolith are reported, incidentally discovered through panoramic radiographs, which showed different sizes of radiopaque images, varying from 2 to 5 mm; cases I and III images did not overlap the mandible ramus, which led to a probable diagnosis of soft tissue calcification. Case II had radiopaque unilateral images, with osseous tissue density, overlapping the mandibular ramus, leading to a benign intra-osseous lesion, which was considered as differential diagnosis. No symptoms were reported in any case. Only case I had clinical characteristics, showing highly consistent white plaques partially visible through the mucosa. Computed tomography of the maxillofacial region/head and neck were requested to find out the exact location of these images, since most of the overlapping radiopaque images in the mandibular ramus were very similar to intra-osseous abnormalities. The computed tomography showed hyperdense images in the palatine tonsils, confirming the diagnosis of tonsillolith. The patients are currently under follow-up. No treatment is required if there is no symptom. In conclusion, tonsillolith might show images on panoramic radiographs similar to intra osseous abnormalities. The diagnosis is relatively easy when computed tomography is requested, although the images are not pathognomonic. Therefore, clinicians should consider other pathologies as differential diagnosis.